Congrates to Xu’s manuscript on Nature communication! Can you believe that over 31,000 protein lysine acetylations in the gut microbiome that are part of regulating the microbiome? Ref: Zhang X, Ning Z, Mayne J, Yang Y, Deeke SA, Walker K, Farnsworth CL, Stokes MP, Couture JF, Mack D, Stintzi A and Figeys D. Widespread protein lysine acetylation […]
New workhorse of Exploris 480 with FAIMS is flying NorthOmics lab. This is going to boost our throughput and scale of metaproteomics analysis.
Congrates to Zikai’s manuscript selected as the cover story on JASMS. Timing is everything, and so it seems for drug effects on the microbiome. This manuscruipt in #JASMS demonstrated that #metformin added during different periods of the growth phase of a #microbiome has distinct effects. https://pubs.acs.org/doi/10.1021/jasms.0c00054… Ref: Hao Z, Li L, Ning Z, Zhang X, […]
Everyday drugs act in surprising ways on the microbiome “Drugs should have two labels—one label for its effect on the host, and another for its effect on the microbiome.”–Dr. Daniel Figeys By Jessica Sinclair, Research Writer A study published today in the journal Microbiome reveals that some of the most commonly taken drugs and compounds can […]
Should drugs, natural compounds, food additives, pesticides and other compounds be tested for effects on the human gut #microbiome ? We now have the in vitro technology, called RapidAIM, to do the testing. Results Here, we developed an approach to screen compounds against individual microbiomes in vitro, using metaproteomics to both measure absolute bacterial abundances […]
Need more depth to your #metaproteomic studies of the gut #microbiome? Check out the paper by Jiaqin Wang et al. on differential lysis of the microbiome in Analytical Chemistry.
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