Congrates to Zikai’s manuscript selected as the cover story on JASMS. 

Timing is everything, and so it seems for drug effects on the microbiome. This manuscruipt in #JASMS demonstrated that #metformin added during different periods of the growth phase of a #microbiome has distinct effects.

Ref: Hao Z, Li L, Ning Z, Zhang X, Mayne J, Cheng K, Walker K, Liu H and Figeys D. Metaproteomics reveals growth phase-dependent responses of an in vitro gut microbiota to metformin. (2020) J. Am. Soc. Mass Spectrom.. PubmedJ. Am. Soc. Mass Spectrom.